For an introduction, Kolchin, American Slavery.
For a sweeping synthesis, Genovese, Roll, Jordan, Roll.
For the three major American slave systems, Berlin, Many Thousands Gone.
For slavery’s cultural impact, Sobel, The World They Made Together.
An excellent and enlightening comparative account is Kolchin, Unfree Labor: American Slavery and Russian Serfdom.
I also quite like Genovese, The Slaveholders’ Dilemma.
The classic treatment of 100+ years ago is Phillips, American Negro Slavery.
Taylor’s The Internal Enemy: Slavery and War in Virginia, 1772-1832 is well written and of inherent interest.
If you want suggestions on any other subtopics, just ask.